Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromomethane SCHEMBL7085054 | 0.97 | KCNN4 (0.38) | KCNN4PDPK1SMN1; SMN2MAPTPPARA | |
| SCHEMBL14142578 | 0.91 | MRGPRX4 (0.34) | KCNN4PDPK1SMN1; SMN2MAPTPPARA | |
| Bromomethane SCHEMBL7086469 | 0.87 | PDPK1 (0.34) | KCNN4PDPK1SMN1; SMN2MAPTHDAC1 | |
| SCHEMBL931372 | 0.83 | CHRM2 (0.39) | KCNN4PDPK1SMN1; SMN2ALDH1A1KCNK3 | |
| SCHEMBL3911903 | 0.82 | KCNN4 (0.41) | KCNN4SMN1; SMN2MAPTALDH1A1HTT | |
| SCHEMBL7086017 | 0.82 | POLB (0.33) | KCNN4PDPK1SMN1; SMN2MAPTHDAC1 | |
| SCHEMBL7081056 | 0.81 | MEN1 (0.36) | KCNN4PDPK1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2027045 | 0.81 | PDPK1 (0.32) | PDPK1SMN1; SMN2MAPTPPARAKCNK3 | |
| SCHEMBL14142466 | 0.81 | CHRM3 (0.34) | KCNN4PDPK1HDAC1ALDH1A1GAA | |
| Bromomethane SCHEMBL118164 | 0.80 | CHRM2 (0.39) | KCNN4SMN1; SMN2PPARAALDH1A1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328524-B1 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-12-12 | — | — | EP | disclosed |
| EP-1328524-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032898-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |