Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142578 | 0.97 | MRGPRX4 (0.34) | PDPK1MRGPRX4POLBNPSR1MAPT | |
| Bromomethane SCHEMBL7085054 | 0.91 | KCNN4 (0.38) | PDPK1MRGPRX4POLBNPSR1MAPT | |
| SCHEMBL7086739 | 0.87 | KCNN4 (0.40) | PDPK1MRGPRX4NPSR1MAPTSMN1; SMN2 | |
| Bromomethane SCHEMBL118164 | 0.84 | CHRM2 (0.39) | POLBSMN1; SMN2KCNN4NPC1RAB9A | |
| Bromomethane SCHEMBL119398 | 0.83 | KCNN4 (0.38) | PDPK1POLBNPSR1MAPTVNN1 | |
| Bromomethane SCHEMBL7085436 | 0.83 | PDPK1 (0.32) | PDPK1MRGPRX4POLBNPSR1MAPT | |
| Bromomethane SCHEMBL120034 | 0.83 | KCNN4 (0.39) | POLBMAPTSMN1; SMN2KCNN4NPC1 | |
| Bromomethane SCHEMBL7081897 | 0.83 | CHRM2 (0.36) | PDPK1POLBNPSR1MAPTSMN1; SMN2 | |
| Bromomethane SCHEMBL7085461 | 0.81 | NPC1 (0.39) | PDPK1POLBMAPTNPC1RAB9A | |
| SCHEMBL931372 | 0.80 | CHRM2 (0.39) | PDPK1POLBSMN1; SMN2KCNN4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328524-B1 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-12-12 | — | — | EP | disclosed |
| EP-1328524-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032898-A2 | NOVEL ANTICHOLINERGICS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |