Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7649996 | 0.99 | PDE7A (0.49) | PDE7AHTR2CSNCAMEN1KMT2A | |
| SCHEMBL29373570 | 0.85 | ALDH1A1 (0.40) | PDE7AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6984818 | 0.85 | ALDH1A1 (0.40) | PDE7AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7081351 | 0.85 | SLC6A2 (0.38) | PDE7ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7654967 | 0.83 | ALDH1A1 (0.39) | PDE7AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7658370 | 0.83 | SLC6A2 (0.37) | PDE7ASLC6A4SLC6A3 | |
| SCHEMBL7085627 | 0.82 | MAOB (0.40) | PDE7AMAOAMAOBALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7661598 | 0.81 | MAOB (0.39) | PDE7AMEN1KMT2AMAOAMAOB | |
| SCHEMBL7083506 | 0.79 | ELANE (0.39) | PDE7AMEN1KMT2A | |
| SCHEMBL10841242 | 0.76 | ALDH1A1 (0.46) | PDE7AHTR2CSNCAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995743-B1 | Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans | SERVIER LAB (FR) | 2003-04-02 | — | — | EP | disclosed |
| US-6350759-B1 | ANTIOXIDATIVE AGENTS FOR OXIDATION STRESS, ESPECIALLY AT THE CEREBRAL LEVEL; | ADIR ET COMPAGNIE (FR) | 2002-02-26 | — | — | US | disclosed |
| EP-0995743-A1 | Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans | ADIR ET COMPAGNIE (FR) | 2000-04-26 | — | — | EP | disclosed |