SCHEMBL7086826

SCHEMBL7086826

Cc1cc(-c2cc(C)c(O)c(C)c2)cc(C)c1O.OCC(Cl)COCC(Cl)CO

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
FYN P06241 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP17A1 P05093 1/20 0.31
SHBG P04278 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7086827 0.76 SCN4A (0.41) CA1CA2CYP1A2CYP2C9
SCHEMBL6361414 0.75 CA1 (0.50) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL7037851 0.73 TP53 (0.47)
Hydroquinone SCHEMBL7086848 0.72 CA2 (0.36) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL7088165 0.72 CA1 (0.42) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL7089768 0.72 ESR1 (0.44) ESR1ESR2
SCHEMBL220910 0.71 CA1 (1.00) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL22804025 0.71 CA1 (1.00) CA1CA2CYP1A2CYP2C9CYP2C19
Resorcinol SCHEMBL7089771 0.70 CYP3A4 (0.46) CA1CA2CYP1A2CYP2C9
SCHEMBL7088386 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030149219-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom BORIACK CLINTON J (US) 2003-08-07 US claimed
US-6534621-B2 Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative DOW GLOBAL TECHNOLOGIES INC. 2003-03-18 US claimed
US-20020045707-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2002-04-18 US claimed