Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DNA2 | P51530 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669408 | 0.94 | TSHR (0.44) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL309038 | 0.87 | TSHR (0.64) | TSHRTDP1L3MBTL1DNA2CASP6 | |
| SCHEMBL27827942 | 0.85 | TSHR (0.62) | TSHRTDP1L3MBTL1DNA2CASP6 | |
| SCHEMBL27287737 | 0.75 | TSHR (0.57) | TSHRTDP1L3MBTL1DNA2CASP6 | |
| SCHEMBL1767333 | 0.74 | TSHR (0.50) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL14895094 | 0.73 | SMN1; SMN2 (0.48) | TDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL14895093 | 0.73 | SMN1; SMN2 (0.48) | TDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL308476 | 0.72 | TSHR (0.49) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL29488320 | 0.72 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL3910666 | 0.72 | TSHR (0.53) | TSHRTDP1L3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203907-A1 | An enzyme inhibitors of cyclin-dependent kinases, antitumor agents; chemical intermediate synthesis | MSD K.K. (JP) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203907-A1 | An enzyme inhibitors of cyclin-dependent kinases, antitumor agents; chemical intermediate synthesis | CDK4, CDK6, CCNI | TSHR 2964/4885TDP1 2621/4885L3MBTL1 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.