Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987830 | 0.81 | ELANE (0.38) | ELANEPGRALDH1A1NPSR1GPR55 | |
| SCHEMBL6618785 | 0.79 | ELANE (0.43) | ELANEALDH1A1NPSR1GPR55MEN1 | |
| SCHEMBL7090352 | 0.77 | ELANE (0.48) | ELANEALDH1A1NPSR1GPR55MEN1 | |
| SCHEMBL7087824 | 0.76 | ELANE (0.46) | ELANEALDH1A1NPSR1GPR55MEN1 | |
| SCHEMBL6615610 | 0.74 | ELANE (0.52) | ELANEPGRALDH1A1NPSR1GPR55 | |
| SCHEMBL6250345 | 0.71 | NR1H4 (0.52) | ELANEMEN1KMT2A | |
| SCHEMBL4851757 | 0.70 | NR1H4 (0.48) | ELANEMEN1KMT2A | |
| SCHEMBL5327298 | 0.69 | NR1H4 (0.45) | ELANE | |
| SCHEMBL4782628 | 0.69 | NR1H4 (0.51) | ELANEMEN1KMT2A | |
| SCHEMBL6205772 | 0.68 | NR1H4 (0.46) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |