SCHEMBL7087340

SCHEMBL7087340

C[N+]1(c2cncn2Cc2ccc(Br)cc2)C=C(C(=O)N2CCOCC2)C(c2cccc3ccccc23)=C1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FNTA P49354 12/20 0.59
FNTB P49356 12/20 0.59
PGGT1B P53609 6/20 0.45
HTR2C P28335 5/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
CYP3A4 P08684 1/20 0.39
APC P25054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7084209 0.93 FNTA (0.51) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL7087362 0.92 FNTA (0.48) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL6974275 0.85 FNTA (0.43) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL7088691 0.84 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL6975064 0.84 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL6982933 0.84 FNTA (0.45) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL6985593 0.82 FNTA (0.44) FNTAFNTBPGGT1BHTR2CLMNA
SCHEMBL7083084 0.82 FNTA (0.47) FNTAFNTBPGGT1B
SCHEMBL7087476 0.81 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP3A4
SCHEMBL6982183 0.80 FNTA (0.46) FNTAFNTBPGGT1BHTR2CCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045846-B1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD (KR) 2003-05-02 EP disclosed
EP-1045846-A1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LIMITED (KR) 2000-10-25 EP disclosed
WO-1999028315-A1 IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF LG CHEMICAL LTD. (KR) 1999-06-10 WO disclosed