Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088417 | 0.92 | CTSK (0.40) | CTSKCCNA2CDK2CCNA1 | |
| SCHEMBL6514175 | 0.89 | CTSK (0.51) | CTSK | |
| SCHEMBL6514338 | 0.87 | CTSK (0.52) | CTSK | |
| SCHEMBL6513836 | 0.82 | CTSK (0.51) | CTSK | |
| SCHEMBL6515438 | 0.80 | CTSK (0.49) | CTSK | |
| SCHEMBL6511602 | 0.80 | CTSK (0.52) | CTSK | |
| SCHEMBL5744818 | 0.80 | CTSK (0.46) | CTSK | |
| SCHEMBL6515235 | 0.79 | CTSK (0.48) | CTSK | |
| SCHEMBL6523338 | 0.79 | CTSK (0.52) | CTSK | |
| SCHEMBL6511255 | 0.78 | CTSK (0.51) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358183-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002088106-A2 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2002-11-07 | — | — | WO | disclosed |