Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559661 | 0.90 | FFAR1 (0.51) | FFAR1MAPTPPARGPPARAMPC2 | |
| SCHEMBL7560832 | 0.87 | FFAR1 (0.52) | FFAR1MAPTSMN1; SMN2PPARG | |
| SCHEMBL6183947 | 0.81 | FFAR1 (0.58) | FFAR1MAPTPPARGPPARAMPC2 | |
| SCHEMBL6184770 | 0.79 | FFAR1 (0.59) | FFAR1MAPTPPARGPPARAMPC2 | |
| SCHEMBL5395849 | 0.79 | FFAR1 (0.57) | FFAR1MAPTPPARGPPARAMPC2 | |
| SCHEMBL7563417 | 0.79 | FFAR1 (0.56) | FFAR1PPARG | |
| SCHEMBL6184667 | 0.77 | FFAR1 (0.59) | FFAR1MAPTSMN1; SMN2PPARGPPARA | |
| SCHEMBL6185534 | 0.76 | FFAR1 (0.65) | FFAR1MAPTPPARGPPARAMPC2 | |
| SCHEMBL6184382 | 0.76 | FFAR1 (0.48) | FFAR1MAPTPPARGPPARAMPC2 | |
| SCHEMBL6480621 | 0.75 | FFAR1 (0.54) | FFAR1MAPTPPARGMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |