Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087432 | 0.87 | FFAR1 (0.48) | FFAR1MAPTSMN1; SMN2PPARG | |
| SCHEMBL7559661 | 0.84 | FFAR1 (0.51) | FFAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6480621 | 0.84 | FFAR1 (0.54) | FFAR1MAPTPPARG | |
| SCHEMBL7563417 | 0.84 | FFAR1 (0.56) | FFAR1PPARG | |
| SCHEMBL6184770 | 0.83 | FFAR1 (0.59) | FFAR1MAPTPPARG | |
| SCHEMBL6187981 | 0.81 | FFAR1 (0.59) | FFAR1MAPTPPARG | |
| SCHEMBL6183947 | 0.80 | FFAR1 (0.58) | FFAR1MAPTPPARG | |
| SCHEMBL6187556 | 0.79 | FFAR1 (0.60) | FFAR1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6182666 | 0.79 | FFAR1 (0.52) | FFAR1MAPTPPARG | |
| SCHEMBL6184201 | 0.78 | FFAR1 (0.57) | FFAR1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |