Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.47 |
| ▸ | ITGAV | P06756 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080713 | 0.85 | ITGB1 (0.46) | ITGB1ITGA5ITGB3ITGAVS1PR1 | |
| SCHEMBL7087451 | 0.85 | ITGB1 (0.44) | ITGB1ITGA5ITGB3ITGAVS1PR1 | |
| SCHEMBL6793279 | 0.83 | POLB (0.47) | ITGB1ITGA5S1PR1S1PR3MAPT | |
| SCHEMBL6677053 | 0.83 | ITGB1 (0.44) | ITGB1ITGA5ITGB3ITGAVS1PR1 | |
| Hydrochloric Acid SCHEMBL6792674 | 0.82 | POLB (0.47) | ITGB1ITGA5S1PR1S1PR3MAPT | |
| SCHEMBL6500761 | 0.80 | ITGB1 (0.43) | ITGB1ITGA5MAPTPOLBTP53 | |
| SCHEMBL7084422 | 0.79 | ITGB1 (0.44) | ITGB1ITGA5POLBGAA | |
| SCHEMBL6499215 | 0.79 | ITGB1 (0.43) | ITGB1ITGA5MAPTPOLBTP53 | |
| SCHEMBL6491904 | 0.79 | ITGB1 (0.43) | ITGB1ITGA5MAPTPOLBTP53 | |
| SCHEMBL6500632 | 0.78 | ITGB1 (0.44) | ITGB1ITGA5MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |