SCHEMBL7087631

SCHEMBL7087631

CCCCCCCc1cc(C)cc(=O)n1O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 18/20 0.54
GPR84 Q9NQS5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7087767 1.00 IDH1 (0.54) IDH1GPR84
SCHEMBL11856342 1.00 IDH1 (0.54) IDH1GPR84
SCHEMBL10934346 1.00 IDH1 (0.54) IDH1GPR84
SCHEMBL10726805 1.00 IDH1 (0.54) IDH1GPR84
SCHEMBL936901 0.81 IDH1 (0.51) IDH1
SCHEMBL7087597 0.79 IDH1 (0.61) IDH1
SCHEMBL3131899 0.79 IDH1 (0.53) IDH1
SCHEMBL7089306 0.78 IDH1 (0.65) IDH1
SCHEMBL11850995 0.75 GPR84 (0.45) GPR84
SCHEMBL15112068 0.75 IDH1 (0.56) IDH1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626862-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2025-10-08 EP claimed
WO-2024115319-A1 PROCESS FOR THE PREPARATION OF N-HYDROXYPYRIDONE COMPOUNDS CLARIANT INTERNATIONAL LTD (CH) 2024-06-06 WO claimed
US-4552754-A Hair cosmetic composition LION CORPORATION (JP) 1985-11-12 US claimed
US-4185106-A Pyridones as antidandruff agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US claimed
US-20030228340-A1 Methods for treating rosacea with pyridones MEDICIS PHARMACEUTICAL CORPORATION 2003-12-11 US disclosed
WO-2003084538-A1 METHODS FOR TREATING ROSACEA WITH PYRIDONES MEDICIS PHARMACEUTICAL CORPORATION (US) 2003-10-16 WO disclosed
US-4711775-A ANTIDANDRUFF HAIR LOTIONS AND SHAMPOOS HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-08 US disclosed
US-4552754-A Hair cosmetic composition LION CORPORATION (JP) 1985-11-12 US disclosed
US-4367169-A α-Olefin sulfonate-containing, liquid detergent compositions having improved low-temperature stability LION CORPORATION (JP) 1983-01-04 US disclosed
US-4185106-A Pyridones as antidandruff agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-3972888-A Process for the preparation of 1-hydroxy-pyridones HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed
US-3968118-A Process for the manufacture of 1-hydroxy-2-pyridones HOECHST AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed