Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946617 | 0.87 | HPGD (0.59) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL1944136 | 0.85 | HPGD (0.47) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7674391 | 0.84 | MEN1 (0.47) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7091654 | 0.81 | MAPT (0.49) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL8578124 | 0.80 | ALDH1A1 (0.51) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7316278 | 0.75 | ALDH1A1 (0.57) | KDM4EKMT2AHPGDALDH1A1MAPT | |
| SCHEMBL1944866 | 0.73 | KMT2A (0.54) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL8576371 | 0.73 | DAO (0.50) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1546582 | 0.72 | MAPT (0.59) | KDM4EMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7088588 | 0.71 | ALDH1A1 (0.74) | KDM4EMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814809-B1 | ARYL THIOXANTHINES | EURO CELTIQUE SA (LU) | 2003-08-13 | — | — | EP | disclosed |
| US-6440979-B1 | Aryl isoguanines | EURO-CELTIQUE, S.A. (LU) | 2002-08-27 | — | — | US | disclosed |
| US-6090816-A | ANTIASTHMA AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-07-18 | — | — | US | disclosed |
| US-6066641-A | PHOSPHODIESTERASES AS MOLECULAR TARGETS FOR ANTI-ASTHMATIC AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-05-23 | — | — | US | disclosed |
| EP-0814809-A4 | ARYL THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | disclosed |
| EP-0814809-A1 | ARYL THIOXANTHINES | Euroceltique S.A. (LU) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996018399-A1 | ARYL THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |