Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 4/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087788 | 1.00 | RET (0.34) | RETPPARACTDSP1TDP1L3MBTL1 | |
| SCHEMBL6977106 | 0.90 | KIT (0.34) | RETPPARAL3MBTL1CTSSMMP13 | |
| SCHEMBL6787549 | 0.90 | KIT (0.34) | RETPPARAL3MBTL1CTSSMMP13 | |
| SCHEMBL6787552 | 0.90 | KIT (0.34) | RETPPARAL3MBTL1CTSSMMP13 | |
| SCHEMBL6782024 | 0.86 | LMNA (0.34) | PPARAMMP13MMP14KDM4EALDH1A1 | |
| SCHEMBL6865711 | 0.86 | PPARA (0.34) | PPARAIDH1RORC | |
| SCHEMBL6782020 | 0.86 | LMNA (0.34) | PPARAMMP13MMP14KDM4EALDH1A1 | |
| SCHEMBL6865714 | 0.86 | PPARA (0.34) | PPARAIDH1RORC | |
| SCHEMBL6786363 | 0.85 | IDH1 (0.37) | PPARACTSSKMT2AKDM4EALDH1A1 | |
| SCHEMBL6786359 | 0.85 | IDH1 (0.37) | PPARACTSSKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-A1 | HYDROXAMIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087870-A1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |