Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823362 | 0.94 | NPY5R (0.66) | NPY5RKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL6828937 | 0.86 | NPY5R (0.67) | NPY5RKDM4EHSD17B10KMT2AHTT | |
| SCHEMBL6826749 | 0.85 | NPY5R (0.65) | NPY5RKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL6826597 | 0.84 | NPY5R (0.64) | NPY5RKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL6823308 | 0.83 | NPY5R (0.62) | NPY5RLMNAKMT2ARAB9AHTT | |
| SCHEMBL6823236 | 0.82 | NPY5R (0.63) | NPY5RKDM4EKMT2AHTTGAA | |
| SCHEMBL6826590 | 0.81 | NPY5R (0.60) | NPY5RKDM4EHSD17B10KMT2ARAB9A | |
| SCHEMBL6829275 | 0.81 | NPY5R (0.69) | NPY5RKMT2ARAB9AHTTMAPT | |
| SCHEMBL6826741 | 0.80 | NPY5R (0.65) | NPY5RKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL6826986 | 0.80 | NPY5R (0.67) | NPY5RKDM4ERAB9AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358157-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |