Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 17/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088278 | 0.87 | SERPINE1 (0.86) | SERPINE1POLB | |
| SCHEMBL7087862 | 0.85 | SERPINE1 (0.58) | SERPINE1ENPP2 | |
| SCHEMBL7088416 | 0.83 | SERPINE1 (0.59) | SERPINE1POLBENPP2 | |
| SCHEMBL7089096 | 0.82 | SERPINE1 (0.62) | SERPINE1 | |
| SCHEMBL7084474 | 0.82 | SERPINE1 (1.00) | SERPINE1POLB | |
| SCHEMBL7084140 | 0.79 | SERPINE1 (0.64) | SERPINE1 | |
| SCHEMBL7087872 | 0.78 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7088054 | 0.77 | SERPINE1 (0.82) | SERPINE1POLB | |
| SCHEMBL30883140 | 0.77 | SERPINE1 (0.61) | SERPINE1POLBENPP2 | |
| SCHEMBL7091835 | 0.76 | SERPINE1 (0.80) | SERPINE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |