Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 14/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090212 | 0.93 | SERPINE1 (0.74) | SERPINE1MEN1KMT2APOLBSIRT6 | |
| SCHEMBL7089619 | 0.92 | SERPINE1 (0.73) | SERPINE1MEN1KMT2APOLBSIRT6 | |
| SCHEMBL7085700 | 0.90 | SERPINE1 (0.76) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7084474 | 0.85 | SERPINE1 (1.00) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7087872 | 0.84 | SERPINE1 (1.00) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7085640 | 0.83 | SERPINE1 (0.61) | SERPINE1MAPTLMNAHTTSIRT6 | |
| SCHEMBL7087727 | 0.82 | SERPINE1 (1.00) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7085481 | 0.82 | SERPINE1 (1.00) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7139738 | 0.81 | SERPINE1 (0.57) | SERPINE1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7088258 | 0.77 | SERPINE1 (0.65) | SERPINE1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |