Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952245 | 0.89 | IDH1 (0.82) | IDH1 | |
| SCHEMBL795981 | 0.84 | IDH1 (0.75) | IDH1 | |
| SCHEMBL10723992 | 0.84 | IDH1 (1.00) | IDH1 | |
| SCHEMBL14140191 | 0.84 | IDH1 (0.66) | IDH1 | |
| SCHEMBL10724937 | 0.81 | IDH1 (0.58) | IDH1 | |
| SCHEMBL9656734 | 0.79 | IDH1 (0.67) | IDH1 | |
| SCHEMBL10726777 | 0.78 | IDH1 (0.74) | IDH1 | |
| SCHEMBL10724894 | 0.78 | KMT2A (0.48) | IDH1 | |
| SCHEMBL9658531 | 0.77 | IDH1 (0.61) | IDH1 | |
| SCHEMBL10563264 | 0.76 | IDH1 (0.63) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552754-A | Hair cosmetic composition | LION CORPORATION (JP) | 1985-11-12 | — | — | US | claimed |
| US-4185106-A | Pyridones as antidandruff agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | claimed |
| US-20030228340-A1 | Methods for treating rosacea with pyridones | MEDICIS PHARMACEUTICAL CORPORATION | 2003-12-11 | — | — | US | disclosed |
| US-4711775-A | ANTIDANDRUFF HAIR LOTIONS AND SHAMPOOS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-08 | — | — | US | disclosed |
| US-4552754-A | Hair cosmetic composition | LION CORPORATION (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4185106-A | Pyridones as antidandruff agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| US-3972888-A | Process for the preparation of 1-hydroxy-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3968118-A | Process for the manufacture of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |