Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672238 | 0.80 | TAAR1 (0.57) | IDO1SLC6A4TAAR1ALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL3027164 | 0.79 | GAA (0.56) | IDO1SLC6A4GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL20394552 | 0.78 | TAAR1 (0.60) | SLC6A4TAAR1GAACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9371761 | 0.78 | TAAR1 (0.55) | IDO1SLC6A4TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL728403 | 0.76 | IDO1 (0.56) | IDO1SLC6A4TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1586966 | 0.76 | TAAR1 (0.56) | SLC6A4TAAR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL62037 | 0.75 | IDO1 (0.59) | IDO1SLC6A4TAAR1GAAALDH1A1 | |
| SCHEMBL1586261 | 0.74 | SLC6A4 (0.66) | IDO1SLC6A4TAAR1CYP1A2CYP2D6 | |
| SCHEMBL1586263 | 0.74 | SLC6A4 (0.66) | IDO1SLC6A4TAAR1CYP1A2CYP2D6 | |
| SCHEMBL1587009 | 0.74 | TAAR1 (0.55) | SLC6A4TAAR1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332138-A1 | RADIOPHARMACEUTICALS FOR DIAGNOSING ALZHEIMER'S DISEASE | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-08-06 | — | — | EP | disclosed |
| WO-2002036581-A1 | RADIOPHARMACEUTICALS FOR DIAGNOSING ALZHEIMER'S DISEASE | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-05-10 | — | — | WO | disclosed |