SCHEMBL62037

SCHEMBL62037

COc1ccc(CSCc2ccc(OC)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.59
ALDH1A1 P00352 1/20 0.56
TP53 P04637 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
ALOX12 P18054 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
APP P05067 1/20 0.55
AGXT P21549 2/20 0.52
LTA4H P09960 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6624910 0.98 IDO1 (0.57) IDO1ALDH1A1TP53CYP3A4ALOX15
Hydrochloric Acid SCHEMBL5797813 0.98 IDO1 (0.60) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL1127531 0.91 LTA4H (0.67) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8406865 0.89 CALM1 (0.63) IDO1SMN1; SMN2APPAGXTLTA4H
SCHEMBL10064850 0.89 IDO1 (0.55) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL12308295 0.89 ALDH1A1 (0.55) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL728403 0.87 IDO1 (0.56) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL7029366 0.87 ALDH1A1 (0.53) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL769511 0.85 IDO1 (0.59) IDO1ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8841051 0.83 IDO1 (0.49) IDO1ALDH1A1TP53CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102558001-B Manufacture the modification method of hydrazides WYETH LLC (US) 2015-09-23 CN claimed
US-20130224211-A1 GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-08-29 US claimed
WO-2012027555-A2 GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-03-01 WO claimed
WO-2008013427-A1 ORGANIC TFTS AND METHOD FOR FABRICATING THE SAME LG CHEM, LTD. (KR) 2008-01-31 WO claimed
US-12558656-B2 Membranes and preparation thereof IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2026-02-24 US disclosed
CN-115772103-B Method for preparing sulfoxide compound by catalytic oxidation of thioether 华东师范大学 2025-04-01 CN disclosed
CN-114401962-B Di-parallel ring compounds as CRBN protein modulators 南京明德新药研发有限公司 2024-05-24 CN disclosed
EP-4139281-B1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES UNIV HEIDELBERG (DE) 2024-05-08 EP disclosed
US-11891448-B2 Glycated CD59 peptides, their preparation, and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-02-06 US disclosed
CN-117024764-A Hemispherical cobalt coordination polymer and composite material, preparation method and application thereof 中原工学院 2023-11-10 CN disclosed
CN-113518805-B Photoinitiator 意大利艾坚蒙树脂有限公司 2023-08-08 CN disclosed
CN-113304775-B Graphene oxide supported molybdenum catalyst with surface chemically grafted, and preparation and application thereof 沈阳药科大学 2023-05-26 CN disclosed
EP-0859770-A1 PROCESS FOR THE SYNTHESIS OF BENZO b]THIOPHENES ELI LILLY AND COMPANY (US) 1998-08-26 EP disclosed
US-5703246-A REACTING AN ORGANOMETALLIC COMPOUND WITH ORGANOSULFUR COMPOUND ZENECA LIMITED (GB) 1997-12-30 US disclosed
WO-1996040676-A1 PROCESS FOR THE SYNTHESIS OF BENZO[b]THIOPHENES ELI LILLY AND COMPANY (US) 1996-12-19 WO disclosed
EP-0724569-A1 PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE ZENECA LIMITED (GB) 1996-08-07 EP disclosed
WO-1995011230-A1 PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE ZENECA LIMITED (GB) 1995-04-27 WO disclosed
US-5196515-A Thiolactone bifunctional chelating agents for diagnostic and therapeutic products THE JOHNS HOPKINS UNIVERSITY (US) 1993-03-23 US disclosed
US-5095111-A Thiolactone bifunctional chelating agents for diagnostic and therapeutic products THE JOHN HOPKINS UNIVERSITY (US) 1992-03-10 US disclosed
EP-0309953-A1 5-Substituted-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methyl-isoxazolidines FISONS CORPORATION (US) 1989-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891448-B2 Glycated CD59 peptides, their preparation, and uses thereof CD59, SIGLEC9, CD209 IDO1 2519/4885ALDH1A1 927/4885TP53 1193/4885
US-12558656-B2 Membranes and preparation thereof EPCAM, B2M, AQP1 IDO1 4703/4885ALDH1A1 3584/4885TP53 4236/4885
US-20130224211-A1 GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF CD59, SIGLEC9, CD209 IDO1 2519/4885ALDH1A1 927/4885TP53 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.