Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675734 | 0.81 | F10 (0.54) | F10 | |
| SCHEMBL7086594 | 0.80 | KDM4E (0.65) | F10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL785158 | 0.79 | F10 (0.53) | F10ITGB3ITGA2B | |
| SCHEMBL7091228 | 0.77 | F10 (0.54) | F10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7089014 | 0.76 | F10 (0.55) | F10 | |
| SCHEMBL5224676 | 0.76 | HDAC3 (0.48) | F10 | |
| SCHEMBL7751783 | 0.76 | CNR1 (0.51) | ALDH1A1 | |
| SCHEMBL7090030 | 0.75 | F10 (0.59) | F10KDM4E | |
| SCHEMBL5868061 | 0.75 | CYP2D6 (0.50) | F10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL27259447 | 0.75 | HTR4 (0.43) | HRH3KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |