Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708329 | 0.80 | TSHR (0.59) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL29573338 | 0.80 | TSHR (0.59) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL10456467 | 0.80 | HTT (0.43) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL16268433 | 0.79 | HTT (0.44) | HTTALDH1A1CYP2C19ANPEPCYP3A4 | |
| SCHEMBL6680371 | 0.78 | HTT (0.50) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL2401582 | 0.78 | HTT (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL5847586 | 0.78 | TAAR1 (0.50) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL23730871 | 0.77 | HTT (0.41) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL19122188 | 0.75 | CYP2C19 (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL17755321 | 0.75 | CYP2C19 (0.46) | HTTALDH1A1CYP2C19CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124786-B2 | Mental-catalyzed process for preparation of substituted pyrazolecarboxamides | BAYER CROPSCIENCE AG (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124786-B2 | Mental-catalyzed process for preparation of substituted pyrazolecarboxamides | BAYER CROPSCIENCE AG (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124786-B2 | Mental-catalyzed process for preparation of substituted pyrazolecarboxamides | BAYER CROPSCIENCE AG (DE) | 2012-02-28 | — | — | US | disclosed |
| EP-2046754-B1 | METHOD FOR PRODUCING ALKYLANILIDES FROM HALOBENZENE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-04-21 | — | — | EP | disclosed |
| US-20100056786-A1 | Method for Producing Alkylanilides from Halobenzene Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056786-A1 | Method for Producing Alkylanilides from Halobenzene Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056786-A1 | Method for Producing Alkylanilides from Halobenzene Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| EP-2046754-A2 | METHOD FOR PRODUCING ALKYLANILIDES FROM HALOBENZENE DERIVATIVES | Bayer CropScience AG (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008006575-A2 | METHOD FOR PRODUCING ALKYLANILIDES FROM HALOBENZENE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008006575-A2 | METHOD FOR PRODUCING ALKYLANILIDES FROM HALOBENZENE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056786-A1 | Method for Producing Alkylanilides from Halobenzene Derivatives | AADAC, CYP4Z1, CYP4X1 | HTT 759/4885ALDH1A1 926/4885CYP2C19 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.