Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088810 | 0.79 | NOTUM (0.47) | KMT2AKDM4EMAPTCYP2A6RAB9A | |
| SCHEMBL5544137 | 0.79 | KMT2A (0.40) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL29044837 | 0.78 | CYP2C9 (0.47) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL24185587 | 0.75 | MEN1 (0.40) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL5544146 | 0.75 | HTT (0.56) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL15352886 | 0.75 | KMT2A (0.40) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL474655 | 0.75 | MAPK1 (0.40) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL15287060 | 0.71 | CASR (0.40) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL24185596 | 0.71 | CASR (0.39) | KMT2AMEN1TSHRKDM4EUSP2 | |
| SCHEMBL15299351 | 0.71 | NPC1 (0.52) | KMT2AMEN1TSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030125325-A1 | Pyrazolyl benzyl thioethers | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-03 | — | — | US | disclosed |
| EP-1273573-A1 | Pyrazolylbenzylthioethers and their use for combating organisms which are harmful to plants | Bayer CropScience AG (DE) | 2003-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125325-A1 | Pyrazolyl benzyl thioethers | TST, TPMT, PTBP3 | KMT2A 3423/4885MEN1 4356/4885TSHR 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.