Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825218 | 0.90 | KCNH2 (0.43) | CD274PDCD1LG2KCNH2NISCHMC4R | |
| Hydrochloric Acid SCHEMBL7738758 | 0.89 | KCNH2 (0.43) | CD274PDCD1LG2KCNH2NISCHMC4R | |
| SCHEMBL6820993 | 0.76 | LMNA (0.42) | CD274PDCD1LG2NISCHLMNA | |
| SCHEMBL6820859 | 0.75 | NISCH (0.42) | CD274PDCD1LG2NISCHPDCD1 | |
| Hydrochloric Acid SCHEMBL7736107 | 0.73 | NISCH (0.49) | CD274PDCD1LG2NISCHLMNA | |
| SCHEMBL6826683 | 0.72 | NISCH (0.36) | CD274PDCD1LG2NISCHPDCD1 | |
| SCHEMBL6824124 | 0.72 | NISCH (0.45) | CD274PDCD1LG2NISCHPDCD1 | |
| SCHEMBL6824307 | 0.72 | NISCH (0.48) | CD274PDCD1LG2NISCHS1PR1 | |
| SCHEMBL6826510 | 0.72 | NISCH (0.52) | CD274PDCD1LG2NISCHPDCD1 | |
| SCHEMBL6824657 | 0.72 | NISCH (0.36) | CD274PDCD1LG2NISCHPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924209-B1 | Hypoglycemic imidazoline compounds | LILLY CO ELI (US) | 2003-05-02 | — | — | EP | claimed |