Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089635 | 0.89 | DRD4 (0.46) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| SCHEMBL5577910 | 0.89 | MCHR2 (0.53) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| SCHEMBL6807533 | 0.79 | MAPK14 (0.53) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| Hydrochloric Acid SCHEMBL5578415 | 0.77 | ACHE (0.57) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| Hydrochloric Acid SCHEMBL7087753 | 0.74 | MAPK14 (0.49) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| SCHEMBL1980829 | 0.73 | HDAC6 (0.53) | SMN1; SMN2NAMPTKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5578392 | 0.72 | ACHE (0.60) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| SCHEMBL27014528 | 0.71 | CCR3 (0.70) | DRD4SMN1; SMN2LMNAMCHR1MCHR2 | |
| SCHEMBL24076570 | 0.70 | SLC6A2 (0.66) | DRD4MCHR1MCHR2MAPT | |
| SCHEMBL30389820 | 0.70 | SLC6A2 (0.66) | DRD4MCHR1MCHR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331010-A1 | PREVENTIVES AND REMEDIES FOR CENTRAL NERVOUS SYSTEM DISEASES | Takeda Chemical Industries, Ltd. (JP) | 2003-07-30 | — | — | EP | disclosed |