Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.66 |
| ▸ | ARNT | P27540 | 12/20 | 0.63 |
| ▸ | EPAS1 | Q99814 | 12/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073313 | 0.81 | KMT2A (0.68) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL15716688 | 0.79 | KMT2A (1.00) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL3503925 | 0.79 | KMT2A (1.00) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL16111786 | 0.79 | KMT2A (0.66) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL4370342 | 0.79 | MEN1 (0.66) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL28411867 | 0.79 | KMT2A (0.71) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL15740027 | 0.78 | ARNT (1.00) | MEN1KMT2AARNTEPAS1MAPT | |
| SCHEMBL15740036 | 0.77 | ARNT (1.00) | MEN1KMT2AARNTEPAS1MAPT | |
| SCHEMBL31557738 | 0.77 | ARNT (1.00) | MEN1KMT2AARNTEPAS1MAPT | |
| SCHEMBL18825636 | 0.76 | KMT2A (0.53) | MEN1KMT2AUSP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405777-B1 | OPTICAL SENSORS FOR DOWNHOLE TOOLS AND RELATED SYSTEMS AND METHODS | BAKER HUGHES HOLDINGS LLC (US) | 2023-03-01 | — | — | EP | claimed |
| EP-3405777-A1 | OPTICAL SENSORS FOR DOWNHOLE TOOLS AND RELATED SYSTEMS AND METHODS | Baker Hughes, a GE company, LLC (US) | 2018-11-28 | — | — | EP | claimed |
| US-10025000-B2 | Optical sensors for downhole tools and related systems and methods | BAKER HUGHES INCORPORATED (US) | 2018-07-17 | — | — | US | claimed |
| WO-2017127411-A1 | OPTICAL SENSORS FOR DOWNHOLE TOOLS AND RELATED SYSTEMS AND METHODS | BAKER HUGHES INCORPORATED (US) | 2017-07-27 | — | — | WO | claimed |
| US-20170212272-A1 | OPTICAL SENSORS FOR DOWNHOLE TOOLS AND RELATED SYSTEMS AND METHODS | BAKER HUGHES INCORPORATED | 2017-07-27 | — | — | US | claimed |
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| EP-3405777-B1 | OPTICAL SENSORS FOR DOWNHOLE TOOLS AND RELATED SYSTEMS AND METHODS | BAKER HUGHES HOLDINGS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| EP-3268362-B1 | SUBSTITUTED PYRIDINES AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| CN-110372550-B | Aryl ethers and their use | 佩洛通治疗公司 | 2021-08-24 | — | — | CN | disclosed |
| US-10807948-B2 | Aromatic compounds and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-10786480-B2 | Combination therapy of a HIF-2-α inhibitor and an immunotherapeutic agent and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| EP-3417851-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3043784-A1 | ARYL ETHERS AND USES THEREOF | Peloton Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| WO-2016057242-A1 | HIF-2α INHIBITORS FOR TREATING IRON OVERLOAD DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-04-14 | — | — | WO | disclosed |
| EP-2919770-A2 | INHIBITION OF HIF-2 HETERODIMERIZATION WITH HIF1 (ARNT) | The Board of Regents of The University of Texas System (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2015035223-A1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2014078479-A2 | INHIBITION OF HIF-2α HETERODIMERIZATION WITH HIF1β (ARNT) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-05-22 | — | — | WO | disclosed |
| WO-2014078479-A2 | INHIBITION OF HIF-2α HETERODIMERIZATION WITH HIF1β (ARNT) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-05-22 | — | — | WO | disclosed |
| US-20030044403-A1 | Anti-infective therapy | GENENTECH, INC. | 2003-03-06 | — | — | US | disclosed |
| EP-0307390-A2 | Chemical compound consisting of cis-3-hydroxyproline for therapeutic treatment, and process for its preparation | MERCKLE GMBH (DE) | 1989-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10786480-B2 | Combination therapy of a HIF-2-α inhibitor and an immunotherapeutic agent and uses thereof | HIF1AN, HIF1A, EGLN2 | MEN1 4089/4885KMT2A 186/4885USP2 696/4885 |
| US-10807948-B2 | Aromatic compounds and uses thereof | VHL, HIF1AN, HIF1A | MEN1 4167/4885KMT2A 510/4885USP2 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.