Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840098 | 0.90 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6491566 | 0.83 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL4840120 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL4847894 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL4849061 | 0.81 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL4848534 | 0.80 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL4848413 | 0.79 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6478538 | 0.79 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL6478278 | 0.79 | ITGAL (0.52) | ITGALITGB2ICAM1 | |
| SCHEMBL4847332 | 0.79 | ITGAL (0.52) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232817-A1 | Small molecules useful for the treatment of inflammatory disease | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232817-A1 | Small molecules useful for the treatment of inflammatory disease | CD74, MSR1, SERPINB1 | ITGAL 1400/4885ITGB2 531/4885ICAM1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.