Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021739 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL7086361 | 0.81 | MAP4K4 (0.58) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL5685526 | 0.81 | NPC1 (0.49) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL7089197 | 0.79 | MAP4K4 (0.42) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL7086560 | 0.79 | MAP4K4 (0.42) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL7090282 | 0.79 | MAP4K4 (0.42) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL7089098 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT | |
| SCHEMBL3946376 | 0.76 | DHODH (0.43) | ALDH1A1MAP4K4MAPTTP53HSD17B10 | |
| SCHEMBL28173307 | 0.75 | CDC7 (0.47) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7086205 | 0.75 | KDM1A (0.49) | ALDH1A1SMN1; SMN2MAP4K4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |