Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644278 | 0.94 | GPR119 (0.68) | GPR119GRIA1LMNASLC6A7CKS1B | |
| SCHEMBL712231 | 0.87 | GPR119 (0.60) | GPR119LMNACKS1BSKP1SKP2 | |
| SCHEMBL6785524 | 0.83 | GPR119 (0.66) | GPR119SLC6A7CKS1BSKP1SKP2 | |
| SCHEMBL20293614 | 0.83 | GPR119 (0.68) | GPR119SLC6A7CKS1BSKP1SKP2 | |
| SCHEMBL15205453 | 0.83 | GPR119 (0.56) | GPR119LMNACKS1BSKP1SKP2 | |
| SCHEMBL5467171 | 0.82 | GPR119 (0.65) | GPR119LMNACKS1BSKP1SKP2 | |
| SCHEMBL6788585 | 0.82 | RET (0.55) | GPR119GRIA1CKS1BSKP1SKP2 | |
| SCHEMBL20293573 | 0.81 | GPR119 (0.58) | GPR119LMNACKS1BSKP1SKP2 | |
| SCHEMBL23810444 | 0.81 | GPR119 (0.56) | GPR119GRIA1LMNACKS1BSKP1 | |
| SCHEMBL20293612 | 0.81 | GPR119 (0.66) | GPR119CKS1BSKP1SKP2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-A1 | HYDROXAMIC ACID DERIVATIVES | Darwin Discovery Limited (GB) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087870-A1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |