SCHEMBL7090579

SCHEMBL7090579

c1ccc2cc(N(c3ccc(-c4ccc(-c5ccc(N(c6ccc7ccccc7c6)c6ccc7ccccc7c6)cc5)cc4)cc3)c3ccc4ccccc4c3)ccc2c1.c1ccc2cc(N(c3ccc4cc(N(c5ccc6ccccc6c5)c5cccc6ccccc56)ccc4c3)c3cccc4ccccc34)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP2A6 P11509 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP1B1 Q16678 2/20 0.34
HIF1A Q16665 1/20 0.34
GSTP1 P09211 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP1A1 P04798 1/20 0.33
MAPK1 P28482 1/20 0.33
MC5R P33032 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18069057 1.00 SIGMAR1 (0.38) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL14111970 1.00 SIGMAR1 (0.38) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL14520007 1.00 SIGMAR1 (0.38) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL10136036 1.00 SIGMAR1 (0.38) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL18069058 0.98 SIGMAR1 (0.39) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL29512089 0.98 SIGMAR1 (0.39) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL17970832 0.98 SIGMAR1 (0.39) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL17471799 0.98 SIGMAR1 (0.39) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL75616 0.98 SIGMAR1 (0.39) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL196148 0.97 SIGMAR1 (0.39) SIGMAR1ESR1ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1396676-B1 Serially connecting OLED devices for area illumination GLOBAL OLED TECHNOLOGY LLC (US) 2018-08-22 EP disclosed
EP-1335638-A1 Organic electroluminescent device having an adhesion-promoting layer for use with a magnesium cathode EASTMAN KODAK COMPANY (US) 2003-08-13 EP disclosed
EP-1333510-A2 Using spacer elements to make electroluminescent display devices EASTMAN KODAK COMPANY (US) 2003-08-06 EP disclosed