Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093600 | 0.85 | CYP11B1 (0.41) | CYP11B1CYP11B2CYP19A1RXRAGRIN1 | |
| SCHEMBL7095208 | 0.80 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1ALDH1A1MAPT | |
| SCHEMBL7093389 | 0.77 | CYP11B1 (0.34) | CYP11B1CYP11B2GRM4NPY5R | |
| SCHEMBL7094263 | 0.77 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1ALDH1A1NPC1 | |
| SCHEMBL7096288 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP19A1ALDH1A1NPC1 | |
| SCHEMBL7094267 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2ALDH1A1MAPTNPC1 | |
| SCHEMBL7090601 | 0.75 | KMT2A (0.44) | CYP11B1CYP11B2ALDH1A1MAPTRAB9A | |
| SCHEMBL7094835 | 0.75 | CLK4 (0.49) | CYP11B1CYP11B2CYP19A1ALDH1A1MAPT | |
| SCHEMBL12094093 | 0.75 | HSP90AA1 (0.35) | CYP11B1CYP11B2ALDH1A1MAPTNPC1 | |
| SCHEMBL7090626 | 0.74 | CYP11B1 (0.36) | CYP11B1CYP11B2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |