Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093370 | 0.87 | KIF11 (0.41) | CYP11B1CYP11B2NPY5RTOP1PDCD1 | |
| SCHEMBL7090607 | 0.77 | CYP11B1 (0.36) | CYP11B1CYP11B2GRM4NPY5R | |
| SCHEMBL7095208 | 0.76 | CYP11B1 (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL6290470 | 0.75 | CYP11B1 (0.47) | CYP11B1CYP11B2HTR1AHTR7KIF11 | |
| SCHEMBL7094267 | 0.75 | CYP11B1 (0.37) | CYP11B1CYP11B2TOP1 | |
| SCHEMBL7090601 | 0.75 | KMT2A (0.44) | CYP11B1CYP11B2KIF11 | |
| SCHEMBL7094263 | 0.73 | CYP11B1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL7096288 | 0.72 | CYP11B1 (0.37) | CYP11B1CYP11B2NPY5RPDCD1CD274 | |
| SCHEMBL7093600 | 0.72 | CYP11B1 (0.41) | CYP11B1CYP11B2CD274 | |
| SCHEMBL7090626 | 0.71 | CYP11B1 (0.36) | CYP11B1CYP11B2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |