Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803946 | 0.79 | AOC3 (0.43) | KMT2AMAPK1HTTKDM4EAOC3 | |
| Hydrochloric Acid SCHEMBL8805153 | 0.78 | AOC3 (0.42) | KMT2AMAPK1HTTKDM4EAOC3 | |
| SCHEMBL7480109 | 0.74 | MAPT (0.45) | MAPK1HTTKDM4EAOC3TSHR | |
| SCHEMBL8807244 | 0.72 | SMN1; SMN2 (0.51) | KMT2AMAPK1KDM4ETSHRMEN1 | |
| SCHEMBL10744946 | 0.72 | HTT (0.45) | MAPK1HTTKDM4ETSHRAPOBEC3A | |
| SCHEMBL8806370 | 0.72 | POLB (0.51) | KMT2AMAPK1KDM4ETSHRMEN1 | |
| Hydrochloric Acid SCHEMBL8904240 | 0.72 | SMN1; SMN2 (0.53) | KMT2AMAPK1KDM4ETSHRMEN1 | |
| SCHEMBL6692844 | 0.71 | HTT (0.42) | MAPK1HTTKDM4ETSHRAPOBEC3A | |
| SCHEMBL19423042 | 0.71 | ALDH1A1 (0.46) | KMT2AMAPK1KDM4EAOC3TSHR | |
| SCHEMBL19423136 | 0.71 | GAA (0.44) | KMT2AMAPK1HTTKDM4ETUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358171-A2 | NOVEL UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE | Aventis Pharma S.A. (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059102-A2 | UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE | AVENTIS PHARMA S.A. (FR) | 2002-08-01 | — | — | WO | disclosed |