SCHEMBL7090747

SCHEMBL7090747

NC(Cc1cccc(Oc2ccccc2)c1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 8/20 0.64
PTGS1 P23219 2/20 0.64
ALPI P09923 1/20 0.64
PKM P14618 1/20 0.64
XIAP P98170 1/20 0.64
PPARG P37231 2/20 0.58
PPARA Q07869 2/20 0.58
GRIA2 P42262 1/20 0.56
KDM4E B2RXH2 1/20 0.55
USP2 O75604 1/20 0.55
EGFR P00533 1/20 0.55
LCK P06239 1/20 0.55
FYN P06241 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
ALOX15 P16050 1/20 0.55
HTR2A P28223 1/20 0.55
PTGS2 P35354 1/20 0.55
RECQL P46063 1/20 0.55
HIF1A Q16665 1/20 0.55
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7444494 1.00 SLC7A5 (0.64) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL7432221 0.98 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL6928261 0.98 SLC7A5 (0.62) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL9541991 0.94 SLC7A5 (0.60) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL5123605 0.91 PCNA (0.62) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL6927075 0.90 SLC7A5 (0.54) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL30381210 0.90 SLC7A5 (0.55) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL5110394 0.90 SLC7A5 (0.55) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL7089811 0.89 SLC7A5 (0.53) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL4597924 0.86 HDAC8 (0.53) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713859-B1 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO CO LTD (JP) 2000-08-30 EP claimed
US-20230357307-A1 CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING ILLUMINA, INC. 2023-11-09 US disclosed
US-20230357307-A1 CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING ILLUMINA, INC. 2023-11-09 US disclosed
US-20030194375-A1 Administering 3-aminopropionic acid derivative as anticonvulsant QUEEN'S UNIVERSITY AT KINGSTON AND NEUROCHEM, INC. 2003-10-16 US disclosed
US-4873253-A Phenylalanine derivative and proteinase inhibitor Okamoto, Shosuke (JP) 1989-10-10 US disclosed
EP-0284632-A1 Phenylalanine derivative and proteinase inhibitor Okamoto, Shosuke (JP) 1988-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194375-A1 Administering 3-aminopropionic acid derivative as anticonvulsant SLC1A2, SLC1A1, SLC1A3 SLC7A5 274/4885PTGS1 662/4885ALPI 1312/4885
US-20230357307-A1 CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING TENT4A, TENT4B, DNTT SLC7A5 1851/4885PTGS1 4767/4885ALPI 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.