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Sugi Predict / Targets / TENT4B

TENT4B

Terminal nucleotidyltransferase 4B · Q8NDF8 · TENT4B on Sugi Atlas →

2,293 patent compounds predicted against TENT4B, 903 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL21327154 SCHEMBL21327154 1.00 1/20
SCHEMBL21327157 SCHEMBL21327157 1.00 1/20
SCHEMBL21327150 SCHEMBL21327150 0.88 1/20
SCHEMBL21327138 SCHEMBL21327138 0.84 1/20
SCHEMBL21327140 SCHEMBL21327140 0.84 1/20
SCHEMBL21327202 SCHEMBL21327202 0.80 1/20
SCHEMBL19953243 SCHEMBL19953243 0.77 1/20
SCHEMBL20876569 SCHEMBL20876569 0.77 1/20
SCHEMBL16929853 SCHEMBL16929853 0.73 1/20
SCHEMBL16942404 SCHEMBL16942404 0.73 1/20
SCHEMBL16942409 SCHEMBL16942409 0.73 1/20
SCHEMBL19924549 SCHEMBL19924549 0.73 1/20
SCHEMBL21043364 SCHEMBL21043364 0.73 1/20
SCHEMBL21327114 SCHEMBL21327114 0.72 1/20
SCHEMBL21327116 SCHEMBL21327116 0.72 1/20
SCHEMBL16930014 SCHEMBL16930014 0.71 1/20
SCHEMBL21043355 SCHEMBL21043355 0.71 1/20
SCHEMBL21327146 SCHEMBL21327146 0.70 1/20
SCHEMBL21327205 SCHEMBL21327205 0.70 1/20
SCHEMBL16929914 SCHEMBL16929914 0.70 1/20

Clinical trials — most relevant to TENT4B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Tumor Gene Expression in Women With Ovarian Cancer PHASE4COMPLETED
A Phase II Study of TX Regimen as First-line Treatment for Asian Elderly Patients With Advanced Adenocarcinoma of Lung PHASE2COMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism nanUNKNOWN
Genetic Investigation of Solid Tumors Cohort nanCOMPLETED
Role of Nitric Oxide in Diabetic Patients With Erectile Dysfunction nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations nanCOMPLETED
Epigenetics, DNA Methylation Patterns and Periodontal Disease nanCOMPLETED
Thoracic Aortic Dilatation Syndromes nanCOMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Retrospective Analysis of Patients With Metastatic Renal Cell Carcinoma Treated With CABOzantinib nanRECRUITING
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
SCOR in Neurobiology of Sleep--Intermediate Traits for Sleep Apnea nanCOMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED
Identification of New Genes Implicated in Rare Neurosensory Diseases by Whole Exome Sequencing nanUNKNOWN
Genetic Analysis of Thyrotoxic Periodic Paralysis nanCOMPLETED
Strain Echocardiography to Predict Cardiotoxicity in Patients Receiving Chemotherapy Containing Doxorubicin nanCOMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion nanRECRUITING
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Characteristics of Idiopathic Familial Voice Disorders nanCOMPLETED
A Study of the Genetic Analysis of Brain Disorders nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TENT4B binder may also engage these)

ProteinNameSimilarity
Q68ED3 — 0.997 Q68ED3 →
Q8VYW1 — 0.982 Q8VYW1 →
Q9LMT2 — 0.982 Q9LMT2 →
O82312 — 0.976 O82312 →
Q6DFA8 — 0.975 Q6DFA8 →
Q9BWT3 — 0.975 Q9BWT3 →
Q6PB75 — 0.973 Q6PB75 →
Q0VFA3 — 0.973 Q0VFA3 →
TENT4A Terminal nucleotidyltransferase 4A 0.973 landscape →
Q641A1 — 0.972 Q641A1 →
Q6PCL9 — 0.972 Q6PCL9 →
Q9LHE4 — 0.971 Q9LHE4 →
Q8S4P6 — 0.971 Q8S4P6 →
Q60GC1 — 0.971 Q60GC1 →
Q5XET5 — 0.970 Q5XET5 →
Q28C33 — 0.970 Q28C33 →
Q6YVY0 — 0.970 Q6YVY0 →
Q9SL49 — 0.970 Q9SL49 →
O22199 — 0.970 O22199 →
Q9C5W3 — 0.969 Q9C5W3 →
Q503I9 — 0.969 Q503I9 →
Q9LR47 — 0.968 Q9LR47 →
KAT2B Histone acetyltransferase KAT2B 0.968 landscape →
Q9XIP2 — 0.968 Q9XIP2 →
Q9AYT5 — 0.968 Q9AYT5 →
Q501H5 — 0.968 Q501H5 →
Q8VHF0 — 0.968 Q8VHF0 →
Q9QXP6 — 0.968 Q9QXP6 →
Q9SI52 — 0.968 Q9SI52 →
Q5JK20 — 0.968 Q5JK20 →