Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | FPR1 | P21462 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 8/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6374214 | 0.92 | USP30 (0.49) | FPR2USP30FPR1NAMPTMMP1 | |
| SCHEMBL6374206 | 0.92 | USP30 (0.49) | FPR2USP30FPR1NAMPTMMP1 | |
| SCHEMBL7088998 | 0.84 | MAPK1 (0.51) | FPR2F10 | |
| SCHEMBL7142205 | 0.83 | FPR2 (0.60) | FPR2USP30F10 | |
| SCHEMBL6380705 | 0.82 | F10 (0.55) | FPR2USP30F10 | |
| SCHEMBL6374074 | 0.82 | F10 (0.55) | FPR2USP30F10 | |
| SCHEMBL6374070 | 0.82 | F10 (0.55) | FPR2USP30F10 | |
| SCHEMBL6374816 | 0.79 | F10 (0.53) | FPR2NAMPTF10 | |
| SCHEMBL6378918 | 0.79 | F10 (0.53) | FPR2NAMPTF10 | |
| SCHEMBL6374808 | 0.79 | F10 (0.53) | FPR2NAMPTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |