Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.74 |
| ▸ | PGR | P06401 | 11/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167693 | 0.92 | NR3C1 (0.73) | NR3C1PGR | |
| SCHEMBL4172407 | 0.89 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL4182449 | 0.89 | NR3C1 (0.79) | NR3C1PGR | |
| SCHEMBL4181559 | 0.87 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL4175393 | 0.87 | NR3C1 (0.79) | NR3C1PGR | |
| SCHEMBL4175446 | 0.87 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL4181244 | 0.86 | NR3C1 (0.77) | NR3C1PGR | |
| SCHEMBL6998074 | 0.86 | NR3C1 (0.83) | NR3C1PGR | |
| SCHEMBL4179406 | 0.86 | NR3C1 (0.75) | NR3C1PGR | |
| SCHEMBL4176184 | 0.85 | NR3C1 (0.75) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299392-A2 | GLUCOCORTIOCOID-SELECTIVE ANTIINFLAMMATORY AGENTS | Abbott Laboratories (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002002565-A2 | GLUCOCORTIOCOID-SELECTIVE ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 2002-01-10 | — | — | WO | claimed |