Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970493 | 0.91 | ERN1 (0.52) | ERN1CDK1 | |
| SCHEMBL29951782 | 0.86 | ERN1 (0.58) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL172664 | 0.86 | ERN1 (0.58) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL8958284 | 0.84 | ERN1 (0.56) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL11407468 | 0.84 | ERN1 (0.56) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL20339320 | 0.84 | ERN1 (0.56) | ERN1KDM4ELMNAMAPTHTT | |
| Hydrazine SCHEMBL28566747 | 0.82 | ERN1 (0.54) | ERN1KDM4ELMNAMAPTHTT | |
| Catechol SCHEMBL28758914 | 0.79 | TRIM24 (0.57) | ERN1KDM4ELMNAMAPTHTT | |
| P-Cresol SCHEMBL9435012 | 0.79 | ERN1 (0.50) | ERN1KDM4ELMNAMAPTHTT | |
| SCHEMBL29121131 | 0.79 | ERN1 (0.50) | ERN1KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334107-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | Basell Polyolefine GmbH (DE) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032908-A2 | NON-METALLOCENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE OF THE SAME FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2002-04-25 | — | — | WO | disclosed |