Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165337 | 0.81 | — | — | |
| SCHEMBL15334613 | 0.80 | KDM4E (0.57) | KDM4EFTOMAP3K5KDM4AKDM4B | |
| Bromide SCHEMBL6153368 | 0.79 | — | — | |
| SCHEMBL27396299 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5744190 | 0.79 | — | — | |
| Water SCHEMBL27535040 | 0.79 | — | — | |
| SCHEMBL11167638 | 0.78 | KDM4E (0.61) | KDM4EFTOMAP3K5KDM4AKDM4B | |
| SCHEMBL10627937 | 0.78 | KDM4E (0.61) | KDM4EFTOMAP3K5KDM4AKDM4B | |
| SCHEMBL4532908 | 0.78 | KDM4E (0.67) | KDM4EFTOMAP3K5KDM4AKDM4B | |
| SCHEMBL2169512 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283831-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-02-19 | — | — | EP | claimed |
| WO-2001090090-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2001-11-29 | — | — | WO | claimed |
| JP-58077886-A | — | — | None | — | — | JP | disclosed |
| CN-114746418-A | Monocyclic beta-lactam compounds and uses thereof | 苏州信诺维医药科技股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| WO-2021115444-A1 | MONOCYCLIC β-LACTAM COMPOUND AND USE THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-17 | — | — | WO | disclosed |
| EP-1283831-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001090090-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2001-11-29 | — | — | WO | disclosed |
| EP-0261503-B1 | HETEROCYCLIC AMIDO DERIVATIVES OF SUBSTITUTED BENZOIC ACIDS AND THERAPEUTIC COMPOSITIONS WHICH CONTAIN THEM AS ACTIVE PRINCIPLE | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1992-04-15 | — | — | EP | disclosed |
| EP-0376724-A2 | Cephalosporin compounds | TANABE SEIYAKU CO., LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
| US-4761409-A | ANTIBIOTICS, BACTERICIDES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-08-02 | — | — | US | disclosed |
| US-4736039-A | ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4649136-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0071891-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0171812-A2 | Cephem derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |
| US-4515788-A | BACTERICIDAL ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-05-07 | — | — | US | disclosed |
| JP-S5877886-A | NOVEL CEPHALOSPORIN | TOYAMA CHEM CO LTD | 1983-05-11 | — | — | JP | disclosed |
| EP-0071891-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
| EP-0006146-B1 | CEPHEM DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-09-15 | — | — | EP | disclosed |
| US-4282220-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |
| EP-0006146-A1 | Cephem derivatives, process for their preparation and pharmaceutical compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |