Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 19/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094059 | 0.85 | IDH1 (0.59) | IDH1 | |
| SCHEMBL7089306 | 0.82 | IDH1 (0.65) | IDH1 | |
| SCHEMBL11822962 | 0.80 | IDH1 (0.62) | IDH1 | |
| SCHEMBL7087597 | 0.78 | IDH1 (0.61) | IDH1 | |
| SCHEMBL4720732 | 0.76 | IDH1 (0.57) | IDH1 | |
| SCHEMBL28952245 | 0.74 | IDH1 (0.82) | IDH1 | |
| SCHEMBL7088337 | 0.74 | IDH1 (0.75) | IDH1 | |
| SCHEMBL10934346 | 0.73 | IDH1 (0.54) | IDH1 | |
| SCHEMBL10723992 | 0.73 | IDH1 (1.00) | IDH1 | |
| SCHEMBL7087767 | 0.73 | IDH1 (0.54) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030228340-A1 | Methods for treating rosacea with pyridones | MEDICIS PHARMACEUTICAL CORPORATION | 2003-12-11 | — | — | US | disclosed |
| WO-2003084538-A1 | METHODS FOR TREATING ROSACEA WITH PYRIDONES | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |
| US-3968118-A | Process for the manufacture of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |