Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088927 | 0.77 | HRH3 (0.42) | HRH3 | |
| SCHEMBL27097480 | 0.77 | HRH3 (0.42) | HRH3 | |
| SCHEMBL7091537 | 0.74 | HRH3 (0.39) | HRH3 | |
| SCHEMBL29889633 | 0.72 | HRH3 (0.42) | HRH3 | |
| SCHEMBL11357218 | 0.71 | GAA (0.36) | — | |
| SCHEMBL4993541 | 0.70 | POLB (0.42) | — | |
| SCHEMBL4989467 | 0.68 | POLB (0.44) | — | |
| SCHEMBL7772650 | 0.68 | — | — | |
| SCHEMBL595778 | 0.66 | CYP2C19 (0.37) | — | |
| SCHEMBL6595312 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270562-A2 | Cyclic alpha-amino-gamma-hydroxy-amides, process for their preparation and pharmaceutical compositions thereof | Les Laboratoires Servier (FR) | 2003-01-02 | — | — | EP | disclosed |