Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 15/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085481 | 0.86 | SERPINE1 (1.00) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7087872 | 0.84 | SERPINE1 (1.00) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7084474 | 0.83 | SERPINE1 (1.00) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7091835 | 0.82 | SERPINE1 (0.80) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7085700 | 0.80 | SERPINE1 (0.76) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7090212 | 0.79 | SERPINE1 (0.74) | SERPINE1MEN1KMT2APOLB | |
| SCHEMBL7089619 | 0.79 | SERPINE1 (0.73) | SERPINE1MEN1KMT2APOLB | |
| SCHEMBL7085002 | 0.76 | MAPT (0.63) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7142564 | 0.74 | SERPINE1 (0.66) | SERPINE1MEN1KMT2APOLBMAPT | |
| SCHEMBL7091114 | 0.73 | SERPINE1 (0.77) | SERPINE1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |