Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.78 |
| ▸ | CNR2 | P34972 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 10/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22500570 | 0.92 | SMN1; SMN2 (0.76) | CNR1CNR2MAPTALDH1A1KMT2A | |
| SCHEMBL22500269 | 0.89 | SMN1; SMN2 (0.81) | CNR1CNR2MAPTALDH1A1KMT2A | |
| SCHEMBL22500330 | 0.87 | SMN1; SMN2 (0.84) | CNR1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30964175 | 0.86 | GAA (0.65) | CNR1CNR2MAPTALDH1A1KMT2A | |
| SCHEMBL30444799 | 0.86 | CNR1 (0.71) | CNR1CNR2MAPTALDH1A1KMT2A | |
| SCHEMBL23000084 | 0.86 | NPC1 (0.77) | CNR1CNR2MAPTALDH1A1KMT2A | |
| SCHEMBL30964189 | 0.86 | L3MBTL1 (0.80) | CNR1CNR2MAPTALDH1A1MAPK1 | |
| SCHEMBL22500270 | 0.85 | POLB (0.76) | CNR1MAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL30964174 | 0.85 | MAPT (0.69) | CNR1CNR2MAPTALDH1A1KMT2A | |
| SCHEMBL22500415 | 0.84 | CNR1 (0.69) | CNR1CNR2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874361-B | Compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2024-07-12 | — | — | CN | claimed |
| WO-2020204548-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | 재단법인 의약바이오컨버젼스연구단 | 2020-10-08 | — | — | WO | claimed |
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |
| CN-113874361-B | Compound with anticancer activity and preparation method thereof | 医药生命融合研究团 | 2024-07-12 | — | — | CN | disclosed |
| WO-2020204548-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | 재단법인 의약바이오컨버젼스연구단 | 2020-10-08 | — | — | WO | disclosed |
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |