SCHEMBL709190

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL705622	0.90	ALDH1A1 (0.53)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL708063	0.90	ALDH1A1 (0.54)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL708489	0.90	KDM4E (0.48)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL710145	0.89	KDM4E (0.50)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL708995	0.89	CRBN (0.51)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL707564	0.85	KMT2A (0.53)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL710666	0.84	MAPT (0.61)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL707263	0.84	KDM4E (0.53)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL710676	0.84	MAPT (0.61)	ALDH1A1KMT2AKDM4EMAPTMEN1
	SCHEMBL6128544	0.84	MAPT (0.61)	ALDH1A1KMT2AKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.