Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436579 | 0.84 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL2436577 | 0.84 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7450093 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7450097 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7970893 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL7970902 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL9512050 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL9512053 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL12469696 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10ALOX15 | |
| O,O'-Dimethylcaffeic Acid SCHEMBL81318 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092865-A1 | Silicone based ultraviolet absorbing and/or scattering compounds and associated formulations comprising the same | SILVER MICHAEL E (US) | 2003-05-15 | — | — | US | disclosed |