Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784873 | 0.86 | S1PR1 (0.40) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6775894 | 0.86 | S1PR1 (0.40) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6782045 | 0.85 | AKR1B1 (0.48) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6775708 | 0.84 | S1PR1 (0.35) | NOTUMS1PR1DHODHS1PR3PLAT | |
| SCHEMBL14606351 | 0.83 | S1PR1 (0.40) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6781208 | 0.81 | S1PR1 (0.39) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6836971 | 0.80 | PLAT (0.37) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6837379 | 0.80 | PLAT (0.37) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6776796 | 0.80 | AKR1B1 (0.38) | S1PR1DHODHS1PR3PLATAKR1B1 | |
| SCHEMBL6841107 | 0.79 | PLAT (0.37) | S1PR1DHODHS1PR3PLATAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | HARMSEN SVEN (DE) | 2003-08-28 | — | — | US | disclosed |
| EP-1140922-A1 | 4-TRIFLUOROMETHYL-3-OXADIAZOLYL PYRIDINES, METHODS FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THESE COMPOUNDS, AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035913-A1 | 4-TRIFLUOROMETHYL-3-OXADIAZOLYL PYRIDINES, METHODS FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THESE COMPOUNDS, AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HCK, HPD | NOTUM 1718/4885S1PR1 2943/4885DHODH 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.