Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 9/20 | 0.41 |
| ▸ | CCKAR | P32238 | 4/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609382 | 0.82 | KCNH2 (0.64) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL7820263 | 0.78 | KCNH2 (0.67) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL8609386 | 0.70 | KCNH2 (0.53) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL8609377 | 0.70 | KCNH2 (0.53) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL8609373 | 0.70 | KCNH2 (0.53) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL6302389 | 0.67 | CCKBR (0.51) | KCNH2CCKBRCCKARPSEN1PSEN2 | |
| SCHEMBL6299832 | 0.67 | SCN9A (0.54) | KCNH2CCKBRCCKARHDAC3HDAC4 | |
| SCHEMBL7808673 | 0.67 | SCN9A (0.52) | CCKBRCCKARGABRPGABRDGABRA1 | |
| SCHEMBL9038949 | 0.65 | CCKBR (0.51) | KCNH2CCKBR | |
| SCHEMBL9039394 | 0.65 | CCKBR (0.66) | KCNH2CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730454-A4 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0730454-A1 | ANTIARRHYTHMIC BENZODIAZEPINES | MERCK & CO. INC. (US) | 1996-09-11 | — | — | EP | disclosed |