Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.68 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.68 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397825 | 0.85 | MAPT (0.68) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29463595 | 0.85 | MAPT (0.68) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29393797 | 0.83 | AKR1B1 (0.70) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL3359780 | 0.81 | MAOB (0.80) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL30285083 | 0.81 | MAOB (0.80) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29394263 | 0.81 | MAPT (0.63) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL27625791 | 0.81 | MAPT (0.63) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29569747 | 0.81 | KDM4E (0.74) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL29355904 | 0.81 | KDM4E (1.00) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Chromocarb SCHEMBL432304 | 0.81 | KDM4E (1.00) | KDM4EUSP2CSNK2A2PTGS1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353915-A2 | THERAPEUTIC CHROMAN COMPOUNDS | AstraZeneca AB (SE) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002055014-A2 | THERAPEUTIC CHROMAN COMPOUNDS | ASTRAZENECA AB (SE) | 2002-07-18 | — | — | WO | disclosed |