Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637635 | 0.86 | CYP1A2 (0.54) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL30184649 | 0.86 | CYP1A2 (0.54) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL10708948 | 0.84 | CYP1A2 (0.56) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| Sulfuric Acid SCHEMBL2519209 | 0.81 | CYP1A2 (0.49) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL73231 | 0.81 | CYP1A2 (0.49) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL17264178 | 0.78 | CYP1A2 (0.58) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL1639476 | 0.78 | CYP1A2 (0.58) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| Hydrochloric Acid SCHEMBL2868061 | 0.76 | CYP1A2 (0.56) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL4979963 | 0.75 | HTR2C (0.50) | CYP1A2HTR2CHTR2BADRA2AMAOA | |
| SCHEMBL407340 | 0.75 | MAPT (0.82) | CYP1A2HTR2CHTR2BADRA2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233967-A4 | PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS | UNIV WASHINGTON (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1233967-A1 | PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001036426-A1 | PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2001-05-25 | — | — | WO | disclosed |