SCHEMBL7092356

SCHEMBL7092356

C=C(C)C(=O)OCCOC.C=C(C)C(=O)OCCOCC

nearest known ligand 0.85

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.85
ALDH1A1 P00352 7/20 0.53
TSHR P16473 6/20 0.53
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ABCB11 O95342 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2B P18089 1/20 0.33
OPRD1 P41143 1/20 0.33
SCN5A Q14524 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36524 0.92 THRB (1.00) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL16504107 0.90 THRB (0.96) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL135538 0.90 THRB (0.68) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL20276249 0.90 THRB (0.68) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL887753 0.90 THRB (0.96) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL8850982 0.90 THRB (0.96) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL2740451 0.90 THRB (0.68) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL20276144 0.90 THRB (0.68) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL11754913 0.90 THRB (0.96) THRBALDH1A1TSHRPOLBAPEX1
SCHEMBL8850621 0.90 THRB (0.96) THRBALDH1A1TSHRPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195108-B1 EMBEDDING MEDIUM SUITABLE FOR THE PREPARATION OF THIN SECTIONS OF EMBEDDED BIOLOGICAL MATERIALS Chemische Werke Lowi Beteiligungs GmbH (DE) 1989-08-16 EP claimed
US-4680362-A Embedding media suitable for the preparation of thin sections of embedded biological materials CHEMISCHE WERKE LOWI GMBH (DE) 1987-07-14 US claimed
US-20030010668-A1 Desiccating container for moisture-sensitive material WEST PHARMACEUTICAL SERVICES, INC. 2003-01-16 US disclosed
US-5947274-A Desiccating container for moisture-sensitive material SMITHKLINE BEECHAM P.L.C. (GB) 1999-09-07 US disclosed
EP-0195108-B1 EMBEDDING MEDIUM SUITABLE FOR THE PREPARATION OF THIN SECTIONS OF EMBEDDED BIOLOGICAL MATERIALS Chemische Werke Lowi Beteiligungs GmbH (DE) 1989-08-16 EP disclosed
US-4680362-A Embedding media suitable for the preparation of thin sections of embedded biological materials CHEMISCHE WERKE LOWI GMBH (DE) 1987-07-14 US disclosed